![Background glow](/themes/custom/zoryve_hcp/images/glow.jpg)
![Hand with small amount of ZORYVE cream on fingertip](/themes/custom/zoryve_hcp/images/hero-photo-before-and-after-1.jpg)
Actor portrayal
![Background glow](/themes/custom/zoryve_hcp/images/glow.jpg)
![Hand with small amount of ZORYVE cream on fingertip](/themes/custom/zoryve_hcp/images/hero-photo-before-and-after-1-mobile.jpg)
Actor portrayal
Before & After
RELIABLE RESULTS WHEREVER PATIENTS NEED IT
ZORYVE cream. Once a day. Anywhere.
Review clinical trial photos of patients with plaque psoriasis treated with ZORYVE
KNEE7
AGE 59, FEMALE
Actual clinical trial patient
Baseline IGA = 3
![Knee before treatment - Baseline IGA = 3](/themes/custom/zoryve_hcp/images/clearance/knee-baseline.jpg)
![Knee - Week 2 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/knee-week-2.jpg)
![Knee - Week 4 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/knee-week-4.jpg)
![Knee - Week 6 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/knee-week-6.jpg)
![Knee - Week 8 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/knee-week-8.jpg)
INFRAMAMMARY CREASE7
AGE 59, FEMALE
Actual clinical trial patient
Baseline I-IGA = 2
![Inframammary Crease before treatment - Baseline I-IGA = 2](/themes/custom/zoryve_hcp/images/clearance/inframammary-crease-baseline.jpg)
![Inframammary Crease - Week 2 I-IGA = 2](/themes/custom/zoryve_hcp/images/clearance/inframammary-crease-week-2.jpg)
![Inframammary Crease - Week 4 I-IGA = 1](/themes/custom/zoryve_hcp/images/clearance/inframammary-crease-week-4.jpg)
![Inframammary Crease - Week 6 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/inframammary-crease-week-6.jpg)
![Inframammary Crease - Week 8 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/inframammary-crease-week-8.jpg)
POWERFUL CLEARANCE IN HARD-TO-TREAT AREAS1
ELBOW7
AGE 58, MALE
Actual clinical trial patient
Baseline IGA = 4
![Elbow before treatment - Baseline IGA = 4](/themes/custom/zoryve_hcp/images/clearance/elbow-baseline.jpg)
![Elbow - Week 2 IGA = 3](/themes/custom/zoryve_hcp/images/clearance/elbow-week-2.jpg)
![Elbow - Week 4 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/elbow-week-4.jpg)
![Elbow - Week 6 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/elbow-week-6.jpg)
![Elbow - Week 8 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/elbow-week-8.jpg)
HEEL7
AGE 53, FEMALE
Actual clinical trial patient
Baseline IGA = 3
![Heel before treatment - Baseline IGA = 3](/themes/custom/zoryve_hcp/images/clearance/heel-baseline.jpg)
![Heel - Week 2 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/heel-week-2.jpg)
![Heel - Week 4 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/heel-week-4.jpg)
![Heel - Week 6 IGA = 0](/themes/custom/zoryve_hcp/images/clearance/heel-week-6.jpg)
![Heel - Week 8 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/heel-week-8.jpg)
SHIN7
AGE 61, FEMALE
Actual clinical trial patient
Baseline IGA = 3
![Shin before treatment - Baseline IGA = 3](/themes/custom/zoryve_hcp/images/clearance/shin-baseline.jpg)
![Shin - Week 2 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/shin-week-2.jpg)
![Shin - Week 4 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/shin-week-4.jpg)
![Shin - Week 6 IGA = 0](/themes/custom/zoryve_hcp/images/clearance/shin-week-6.jpg)
![Shin - Week 8 IGA = 0](/themes/custom/zoryve_hcp/images/clearance/shin-week-8.jpg)
6x more patients with knee or elbow involvement achieved IGA of Clear (0) or Almost Clear (1) with ZORYVE (49%, n=446) vs vehicle (8%, n=226)11
CLEARANCE ANYWHERE PATIENTS NEED IT7
FACE & NECK7
AGE 54, MALE
Actual clinical trial patient
Baseline IGA = 3
![Face & Neck before treatment - Baseline IGA = 3](/themes/custom/zoryve_hcp/images/clearance/face-neck-baseline.jpg)
![Face & Neck - Week 2 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/face-neck-week-2.jpg)
![Face & Neck - Week 4 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/face-neck-week-4.jpg)
![Face & Neck - Week 6 IGA = 0](/themes/custom/zoryve_hcp/images/clearance/face-neck-week-6.jpg)
![Face & Neck - Week 8 IGA = 1](/themes/custom/zoryve_hcp/images/clearance/face-neck-week-8.jpg)
AXILLA7
AGE 60, MALE
Actual clinical trial patient
Baseline I-IGA = 3
![Axilla before treatment - Baseline I-IGA = 3](/themes/custom/zoryve_hcp/images/clearance/axilla1-baseline.jpg)
![Axilla - Week 2 I-IGA = 3](/themes/custom/zoryve_hcp/images/clearance/axilla1-week-2.jpg)
![Axilla - Week 4 I-IGA = 2](/themes/custom/zoryve_hcp/images/clearance/axilla1-week-4.jpg)
![Axilla - Week 6 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/axilla1-week-6.jpg)
![Axilla - Week 8 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/axilla1-week-8.jpg)
AXILLA7
AGE 37, MALE
Actual clinical trial patient
Baseline I-IGA = 3
![Axilla before treatment - Baseline I-IGA = 3](/themes/custom/zoryve_hcp/images/clearance/axilla2-baseline.jpg)
![Axilla - Week 2 I-IGA = 1](/themes/custom/zoryve_hcp/images/clearance/axilla2-week-2.jpg)
![Axilla - Week 4 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/axilla2-week-4.jpg)
![Axilla - Week 6 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/axilla2-week-6.jpg)
![Axilla - Week 8 I-IGA = 0](/themes/custom/zoryve_hcp/images/clearance/axilla2-week-8.jpg)
3 out of 4 patients achieved I-IGA of Clear (0) or Almost Clear (1) in intertriginous areas with ZORYVE (75%, n=116) vs vehicle (23%, n=63)7
Meaningful clearance at Week 8
These patients met 2-grade improvement on IGA score but did not achieve Clear (0) or Almost Clear (1) at Week 8.7
KNEE7
AGE 60, MALE
Actual clinical trial patient
Baseline IGA = 4
![Knee before treatment - Baseline IGA = 4](/themes/custom/zoryve_hcp/images/clearance/individual-knee-baseline.jpg)
![Knee - Week 8 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/individual-knee-week-8.jpg)
Week 8 IGA = 2
HAND7
AGE 50, MALE
Actual clinical trial patient
Baseline IGA = 4
![Hand before treatment - Baseline IGA = 4](/themes/custom/zoryve_hcp/images/clearance/individual-hand-baseline.jpg)
![Hand - Week 8 IGA = 2](/themes/custom/zoryve_hcp/images/clearance/individual-hand-week-8.jpg)
Week 8 IGA = 2
![Did you know? Banner Image](/themes/custom/zoryve_hcp/images/did-you-know-mobile.png)
![Did you know? Banner Image](/themes/custom/zoryve_hcp/images/did-you-know-desktop.png)
In a 2021 survey of >500 plaque psoriasis patients, more than 4 OUT OF 5 TOPICAL USERS (81%) wished they had more topical treatment alternatives to steroids.7*
*This survey was conducted online by The Harris Poll on behalf of Arcutis Biotherapeutics among US adults 18+ who have been diagnosed with psoriasis by a healthcare provider. The survey was conducted in 2021, among 507 plaque psoriasis patients. Figures were weighted where necessary to bring the data into line with actual proportions in the population using a multistep weighting process.
ZORYVE is for topical use only and not for ophthalmic, oral, or intravaginal use.1